Did Izzie and George die, or will they be back next season?“We will definitely answer those questions in the fall," says creator Shonda Rhimes. "As with anyone you come to love, you don’t want to see them die, but it’s all part of the circle of life.” Still, she allows, “there are some top-notch doctors at Seattle Grace and although there may not be miracles, there could be some good medicine.” And the Season 5 finale did have a bright side: Christina and Hunt are on again, Callie and Arizona are forging a deeper girlfriend-ship, and Der and Mer had a Post-It note wedding. “I wanted you to feel happy for some people,” says Rhimes, noting that “Meredith, our dark and twisty girl, is whole and healed.”